Pediatric Molecular Imaging Team
Heike Daldrup-Link, MD, PhDProfessor of Radiology and by courtesy, of Pediatrics
Director, Pediatric Molecular Imaging, Molecular Imaging Program at Stanford
Co-Director, Cancer Imaging & Early Detection Program, Stanford Cancer Institute
As a physician-scientist being involved in the clinical care of pediatric patients and developing novel imaging technologies in a basic science lab, my goal is to link the fields of Nanomedicine, Cell Biology and Medical Imaging towards more efficient diagnoses and image-guided therapies. Our research team successfully translated numerous nanomedicine technologies from preclinical research concepts to clinical applications, thereby creating direct value for our patients.
Mairead Barroso, MAAdministrative Associate
As an administrative assistant and research administrator I work with the Daldrup-Link Lab to facilitate grant proposals and management. I also coordinate with Dr. Daldrup-Link and her lab members to manage ongoing and upcoming studies ensuring
that they are compliant with university and sponsor policies.
| Phone: (650) 725-2548
Laura J. Pisani, PhDMR Physicist
Member, Molecular Imaging Program at Stanford (MIPS)
Stanford University School of Medicine
As an MRI Physicist, I support the Daldrup-Link lab in development of non-invasive MRI techniques and clinical data analysis for in vivo diagnosis of immune responses to solid organ transplants. I provide monthly Introductory MRI seminars; hands-on
training for MRI, micro-PET, fluorescence imaging; and help optimize experimental design and image data analysis.
| Phone: (650) 498-7865 |
Edwin Chang, PhDDirector of the Preclinical Imaging Facility at the Canary Center
I previously worked at Geron Corporation (Menlo Park, California) where I studied the mechanism of cellular immortalization and cellular aging with the goal to develop new therapies against cancer. I joined Stanford University in 2002 and the Molecular Imaging Program at Stanford (MIPS) in 2009, where I explored the applicability of various modalities (PET, BLI, CT, MRI, US) for many projects related to cancer under the leadership of Sanjiv Sam Gambhir. Most recently, I joined the Daldrup-Link lab where I continue to investigate new cell therapies for the treatment of glioblastoma with multi-modality imaging techniques. Since, July 2020, I have been appointed Director of the Canary Core Preclinical Imaging Facility at the Canary Center of Stanford, Stanford University.
Elizabeth Hawk, MD, PhDRadiologist
Dr. Hawk is a Nuclear Medicine Physician and Neuroradiologist. Following an undergraduate degree in Molecular Cell Biology at UC Berkley, Dr. Hawk completed a master's in medical radiation physics and a PhD in Neuroscience at The Chicago Medical School (RFUMS). She then completed her medical doctorate, residency and dual fellowship requirements at the University of Southern California (USC) and is now dual board certified in Nuclear and Molecular Medicine as well as Radiology. Currently, Dr. Hawk’s research focuses on artificial intelligence applications in patient centered care and the ethical challenges in artificial intelligence adaptation.
She holds several national leadership positions in organized medicine and is a proud member of the RADequal board, promoting diversity in medical informatics. Dr. Hawk is also faculty for the ACR Radiology Leadership Institute.
Lisa Adams, MD, PhDRadiologist
As a radiologist and clinical scientist, I am interested in the development, translation and clinical validation of new medical imaging techniques. My research interests revolve around vascular and oncologic imaging, with particular emphasis on the study of novel MRI techniques, radiomics, and computer vision. I conducted research in molecular MRI and investigated the development and evaluation of methods to improve visualization of the extracellular matrix. I also evaluated quantitative MRI sequences, particularly with respect to their suitability for renal and prostate oncologic imaging, and applied methods from the fields of radiomics and artificial intelligence to improve the diagnostic value of radiologic imaging.
Lucia Barratto, MDResearch Scientist
I am interested in novel clinical imaging technologies for cancer staging and re-staging, such as whole body diffusion weighted MRI and PET/MR imaging, in conjunction with applications of iron oxide nanoparticles as contrast agents. My current projects involve comparisons of different whole body imaging techniques for therapy monitoring in pediatric patients with malignant tumors and investigations of chemotherapy-induced tissue injuries in pediatric cancer survivors.
Mohammad Javad Hajpour, PhDResearch Scientist
I work as a research scientist in the Department of Radiology at Stanford University. My research interest focuses on the nanoparticle design strategies for targeted delivery of drug and/or diagnostic agents to tissues/cells of interest, immunotherapy of cancer, molecular imaging of cancer, regenerative medicine, protein-nanoparticle interaction and protein corona formation, protein/peptide fibrillation, and neurodegenerative diseases. My goal is to develop the nanotechnology-based approaches for diagnosis and treatment of diseases and address the challenges of diverse application of nanomedicine. Currently at Stanford, I am working on the development of new imaging tools for arthritis diagnosis.
Wei Wu, PhDPostdoctoral Research Fellow
I am interested in linking the fields of cell biology and imaging sciences to advance our understanding of human health and disease. I want to explore and uncover fundamental mechanisms that affect the physiology and function of specific cell populations in living organisms.
Ali Rashidi, MDPostdoctoral Research Fellow
I am interested in musculoskeletal imaging. One major concern for successful outcomes of stem cell therapies is the cell fate after implantation. My ultimate goal for stem cell research is to develop clinically applicable, non-invasive and repeatable imaging approaches which can be used for long-term tracking of transplanted stem cells. I also work on development and testing of nanoparticles for clinical imaging of bone metastases with MRI and PET.
Ching-Hsin Huang, PhDPostdoctoral Research Fellow
I am a material scientist and received my Ph.D. from UC San Diego while exploring the delivery of immuno-modulators and viral genes. My current research interests include developing nanotechnology to overcome the limitations of small-molecular therapeutics and navigate therapeutic drugs across biological barriers, and utilizing multimodal imaging to monitor enzyme-activatable theranostic (combined diagnostic and therapeutic) nanoparticles.
Raheleh Roudi, PhDPostdoctoral Research Fellow
I am a research scientist in the Department of Radiology at Stanford University. I worked as an Assistant Professor at the Iran University of Medical Sciences, Iran from 2015 to 2019, before coming to the United States. During this time, I worked on several projects which have led to successful collaborations with the Karolinska Institute; Charite University Hospital in Berlin; Oslo University Hospital; National University of Singapore; Shanghai University of Traditional Chinese Medicine and University of Brescia, among other internationally recognized institutions. I was a visiting scientist at the University of Texas at San Antonio and then appointed as a postdoctoral research associate at the University of Minnesota for one year, before joining Stanford University in 2022. At Stanford, I investigate novel immunotherapies for osteosarcomas with ferumoxytol-MRI and PET/MRI. My research interest focuses on molecular imaging, molecular oncology and immunotherapies of solid tumors. I published more than 40 peer reviewed scientific manuscripts thus far.
Shakthi Kumaran Ramasamy, MDPostdoctoral Research Fellow
I am interested in clinical and translational research to investigate new immunotherapies for osteosarcoma and nanoparticle labelled CAR-T cell therapy for GBM. Therapeutic CAR-T cells face a distinct set of hurdles in the therapy of solid tumors, that does not present in hematopoietic malignancy. My goal is to establish real-time clinical-imaging techniques for image-guided immunotherapy of CAR-T cells and regionally deliver them to the tumor microenvironment through a catheter or direct needle-based injection approach and get those cells where they needed to be! I also work on PET/MR imaging of stem cell transplants in arthritic joints and novel whole-body PET/MR imaging studies for monitoring cancer therapy response in pediatric cancer patients.
Joe Gerald Jesu Raj, PhDPostdoctoral Research Fellow
I completed a PhD in Applied Chemistry, specializing in Inorganic and Organometallic Chemistry and I earned another PhD in Materials Science from the National Institute of Scientific Research, Canada, specializing in Bio-nanotechnology, with special focus on using near infrared based photonic upconverting nanoparticles (UCNPs) for bio/chemical sensors and applications of such materials for producing active radicals for phototherapy. My research interests include analytical and bio-analytical chemistry, organic, inorganic/organometallic synthesis, carbon dots, and polymer nanoparticles for biomedical and biopharmaceutical applications. I previously completed postdoctoral trainings at the Fred and Pamela Buffett Cancer Center of the University of Nebraska Medical Center (UNMC) in Omaha, Tisch Cancer Institute of Icahn School of Medicine at Mount Sinai, New York. Prior to Stanford, I worked at the Perelman School of Medicine, University of Pennsylvania. Currently at Stanford, I am working on the use of smart, tumor enzyme-activatable nanomaterials for brain tumor diagnosis and therapy, using MRI and intravital microscopy (IVM). I have strong background in translational research using animal models in the field of neuro-oncology/imaging.
Manoj Kumar, PhDPostdoctoral Research Fellow
My curiosity is in visualizing the biological characteristics of malignant tumors using non-invasive imaging approaches such as PET and MRI. These imaging modalities enable imaging-guided treatment identifying the molecular signatures of cancer, thus individually tailoring treatment plans for patients. During my doctoral training, I developed a PET imaging approach to evaluate endocrine therapy responses in breast cancer. Since then, I have expanded my research interest to a variety of other solid cancers, including prostate cancer and bone sarcomas. My current research focuses on assessing immunotherapy response by visualizing tumor immune markers. The ultimate goals are to develop new PET and MR imaging probes and more effective immunotherapy approaches for image-guided cancer therapies. To achieve this, I am presently employing antibody-based PET imaging and therapeutic strategies to modulate immune functions and restore the suppressed immune response against cancer cells. I collaborate with interdisciplinary scientists focused on translating preclinical findings into clinical studies. My long-term goal is to be an independent translational scientist focused on developing new imaging and therapeutic strategies in cancer.
Amir H. Sarrami, MDPostdoctoral Research Fellow
I am a radiologist interested in clinical applications and integration of machine learning models with medical imaging studies of cancer. On the clinical side of the Daldrup-Link lab, I am working on PET/MR imaging of lymphoma patients to develop an artificial intelligence algorithm that can assess the treatment response in children with lymphoma.
Wipawee Morakote, MDVisiting Scholar
I am a visiting scholar in the Daldrup-Link lab at Stanford Radiology. I am a pediatric radiologist from the Chiang Mai University, Thailand. My chief interest is to learn about advanced imaging techniques for pediatric oncology applications. I am currently observing and participating in research projects that investigate the role of advanced MRI and whole body PET/MR technologies for the diagnosis and long-term follow up of cancer in children with the to improve the diagnostic accuracy and treatment monitoring of pediatric cancers.
Tina HoVisiting Student
I am a software engineer and visiting student in the Daldrup-Link lab. I plan to pursue a medical degree in the near future and am exploring ways that I can utilize my tech skills to bridge the tech gap in the healthcare field. I am interested in learning more about the cross-section of medicine and machine learning — especially in the context of medical imaging to help diagnose patients.